Ascorbate and Aldarate Metabolism Service

v-innovate Technologies, as a leading biotechnology company, provides reliable, rapid and cost-effective ascorbate and aldarate metabolism analysis service in animal. We leverage our experience, expertise, and technologies to accelerate your scientific research of ascorbate and aldarate metabolism analysis in animal.

Overview

Ascorbate and aldarate metabolism is one of important carbohydrate metabolic pathways and can protect cells against oxidative damage resulting from aerobic metabolism and a range of pollutants. Ascorbate and aldarate metabolism likely affect the oxidative stress response which is closely involved in transformation of L-urobilinogen from L-Urobilin, both of which is related to the oxidative stress. The oxidative stress stimulates the generation of reactive oxygen species, which is closely associated to a lot of pathologies of diseases and disorders such as cardiovascular disease, cancer, aging, and various neurodegenerative diseases. It would not be surprising that aberrant ascorbate and aldarate metabolism links to various diseases and disorders by interfering with oxidative stress. As a high-throughput tool, ascorbate and aldarate metabolism analysis provides a powerful way to diagnosis and gain new insights in disease mechanism or treatment. With integrated array of separation, characterization, identification and quantification experience, v-innovate Technologies provides reliable, rapid and cost-effective ascorbate and aldarate metabolism analysis service for your various scientific purposes.

The Main Applications of Glycolysis Metabolism Service

Biomarker discovery

Disease diagnostics

Drug discovery

Food safety

Metabolic disease research

Advantages of Our Glycolysis Metabolism Service

Rich experience in different types of animal sample preparation

State of art facilities

Professional experiment design and data analysis

Competitive price

Short turnaround time

High accuracy, specificity, and sensitivity

Service Workflow

The and needs for optimal results.

The ascorbate and aldarate metabolism service provided by v-innovate Technologies is based on our cutting-edge chromatographic separation and mass spectrometry platforms. The experimental workflow involves 4 steps: sample collection, metabolites extraction, MS data analysis and bioinformatics analysis (Figure 1). Our service will be tailored to specific samples and needs for optimal results.

Figure 1. The overall workflow of ascorbate and aldarate metabolites service.

List of Detectable Ascorbate and Aldarate Metabolism at v-innovate Technologies

Dehydroascorbic acid	2,3-diketo-L-gulonate	L-lyxonate
L-erythrulose	Oxalate	Threonate
Oxidized glutathione

Sample Requirements

We can analyze any biological materials including but not limited to cells and solid tissues from humans and animals, such as mice, rats, rabbits. If you need transport your samples to us, please follow the below requirements for different types of sample:

• Blood/plasma: 500ul/sample
• Urine: 1ml/sample
• Tissue: 200mg/sample
• Cells: 1x10⁷/sample
• Feces: 500mg/sample
• Shipment condition: dry ice

Report Delivery

• Experimental procedures
• Instrument parameters of liquid chromatography and mass spectrometry
• MS raw data files and the summary of mass spectrometry data quality
• The identification/quantification of lipidic molecules data
• Bioinformatics analysis report (PCA, KEGG, etc.)

Equipped with advanced mass spectrometry for the determination of ascorbate and aldarate metabolism, powerful bioinformatic analysis software and a panel of experienced technicians and scientists, we provide customer-tailored ascorbate and aldarate metabolism analysis service with rapid experimental procedures and easy to read report, to advance your scientific research.

References

1. Sun Lili, Jia Hongmei, Li Jiaojiao, et al. Cecal Gut Microbiota and Metabolites Might Contribute to the Severity of Acute Myocardial Ischemia by Impacting the Intestinal Permeability, Oxidative Stress, and Energy Metabolism. Front Microbiol. 2019, 10:1745.
2. Brieger K, Schiavone S, Miller FJ, Krause K-H. Reactive oxygen species: from health to disease. Swiss Med Wkly. 2012, 142: w13659.